7 January-1 February 2019

All lectures, tutorials and practicals are planned on the Tuesdays and the Fridays.


This module is the first module on HTA. It provides an in-depth explanation of full economic evaluations in all its steps based on effectiveness studies (cohort studies, case-control studies, randomised controlled trials).

Course coordinator

Prof. Silvia Evers, PhD, Department of Health Services
T +31 (0)43-3881602




Regular master’s fee or €1752 (non-master student)

RHS4021 - General Principles of HTA and Trial-based Evaluation

Due to increasing economic concern, health policymakers need to efficiently allocate resources or select cost-effective health interventions Health technology assessment (HTA) – a multidisciplinary research field to evaluate the social, economic, organizational, and ethical issues of a health intervention (e.g. drugs, medical devices, public health) – aims to facilitate this decision-making process to inform how to obtain value for money. HTA is a policy-oriented form of research designed to inform decision-makers on the relative effectiveness or cost-effectiveness of a new technology compared to current or best practice. Within HTA, model-based and trial-based economic evaluations exist. This module focuses on trial-based economic evaluations.

This course will teach you the basic principles of HTA. The course consists of eight tutorials, each covering a unique and essential topic within HTA in logical order: 1) Theoretical framework, 2) Framing, 3) Costs, 4) Outcomes, 5) Analysis, 6) Variability and Uncertainty, 7) Transparent reporting and Bias, 8) Health care decision making.

After this course, you are able to understand and develop trial-based economic evaluations. In addition, you are able to judge the quality, strengths and weaknesses of new developments in the field of HTA. Your knowledge will be tested by a written exam and an oral presentation about your own research proposal for a trial-based economic evaluation.